Principles of Neuroimaging B - 2011
Principles of Neuroimaging B, Winter, 2010 - Class Schedule and Syllabus
Lecture Videos
- Monday 1-3-11 - MR Signals and Contrast Speaker Mark Cohen
- Wednesday 1-5-11 - MR Spatial Encoding I Speaker Mark Cohen
- Wednesday 1-5-11 - MR Spatial Encoding II Speaker Mark Cohen
- Monday 1-10-11 - fMRI and Diffusion Speaker Mark Cohen
- Wednesday 1-12-11 - fMRI Image Quality and Artifacts Speaker Mark Cohen
Week 1 Magnetic Resonance Imaging
Magnetic Resonance Imaging (MRI) is probably the most influential and most felxible current means of imaging the human brain. It features a vast number of separable contrast mechanisms, and a near ideal combination of non-invasiveness, safety, resolution and metric accuracy. However, it is extraordinarily expensive and has limited temporal resolution, especially for functional studies.
Monday 1/3/11 - MR Signals and Contrast. Speaker: Cohen
I will be speaking from these slides
Required Readings
- These notes by Joseph Hornak are highly professional and complete coverage of MRI.
- eMRI is another excellent online MRI learning resource
- Erwin Hahn - Spin Echoes: Essential reading for the MRI community
above: Figure 1 from Hahn, 1950
Suggested Further Reading
- READING
Wednesday 1/5/11 - MRI. Speaker: Daniel Ennis
OUTLINE Required Readings
- READING
Suggested Further Reading
- This week we concern ourselves with nitty-gritty issues in MRI and with the important application of functional MRI.
Week 2 Practical MRI
WEEKLYSUMMARY Updated 1/10/11 - Problem set 1 is due 1/19/2011.
Monday 1/10/11 - MRI Artifacts & fMRI. Speaker: Cohen
OUTLINE
Required Readings
Suggested Further Reading
- READING
Wednesday 1/12/11 - fMRI. Speaker: Cohen
OUTLINE Required Readings
Suggested Further Reading
- READING
Week 3 Advanced MRI Sequences
We are fortunate to feature Jin Hyung Lee, a recently added faculty member at UCLA. Dr. Lee has pioneered many novel technologies and applications of MRI, with special applications to neuroscience.
Monday 1/17/11 - Martin Luther King Holiday.
Suggested Further Reading
Wednesday 1/19/11 - Steady state and other advanced sequences. Speaker: Jin Hyung Lee
OUTLINE Required Readings
Suggested Further Reading
Week 4 Applied fMRI, Diffusion Tractography
There is enormous subtlety to the design of pyschophysical and psychological studies made more complex by fitting the experiments into the constrained environment of the MR instrument, the limitations of the BOLD signal and the practical problems of time. This week, Dr. Bookheimer will introduce the design of human functional imaging experiments from the point of view of exposing cognitive process using fMRI.
Monday 1/24/11 - Experimental Design. Speaker: Susan Bookheimer
OUTLINE Required Readings
Suggested Further Reading
Wednesday 1/26/11 - Tractography using MRI Diffusion. Speaker: Nathan Hageman
OUTLINE Required Readings
Suggested Further Reading (from Nate)
- Sadly, the library does not have a subscription for the journals below (Mark has copies on reserve in his office):
Week 5 MEG, EEG, Low Field MRI
Dr. Simpson is a leading expert in the use of scalp electrophysiology (EEG and MEG) to explore the dynamical processes of the human brain, and the integration of activity across cortex in complex human behaviors. Notably, the MEG instrument also uses the SQUID technology
Konstantin Penanen, together with Inseob Hahn and Byeong Ho Eom, have created a highly unusual MR imaging instrument that collects data in a magnetic field less than that of the earth. The tool uses Superconductin QUantum Interference Devices (SQUIDs) that detect the magnetic resonance imaging signal by direct magnetometry, rather than by induction.
Monday 1/31/11 - MEG and EEG. Speaker: Greg Simpson
Monday 2/2//11 - Ultralow field MRI. Speaker: Konstantin Penanen NASA/CalTech Jet Propulsion Laboratory
OUTLINE
Required Readings
- READING
Suggested Further Reading
- READING
Required Readings
- READING
Suggested Further Reading
- READING
Week 6 PET and TMS
Positron Emission Tomography was the first tomographic means available to explore neural activity in humans. Though this use was made much less common with the advent of fMRI, PET has many tricks up its sleeve. In particular, the technology allows incomparable sensitivity in the localization specific molecular species.
Transcranial Magnetostimulation is fundamentally different than the other technologies we have explored, in that it is used specifically to alter ongoing brain activity. While not exactly an imaging method, the TMS instrument is image-guided and uses tomographic placement.
Monday 2/7/11 - Positron Emmission Tomography (PET) Applications. Speaker: Edythe London
OUTLINE
Required Readings
- READING
Suggested Further Reading
- READING
Wednesday 2/9/11 - Transcranial Magneto Stimulation (TMS). Speaker: Allan Wu
OUTLINE Required Readings
Suggested Further Reading
- READING
Week 7 Spectroscopy and PET
Both PET and MRI are means of localizing specific molecular species. MRI has lower sensitivity but good quantitative accuracy and the ability to simultaneously image and study multiple molecules and compounds. Our lecture on PET will consider the actual imaging device, its sensitivity and its limitations.
Monday 2/14/11 - Magnetic Resonance Spectroscopy. Speaker: Jeffry Alger
OUTLINE Required Readings
Suggested Further Reading
- READING
Wednesday 2/16/11 - Positron Emission Tomography (PET) Applications. Speaker: Magnus Dahlbom
OUTLINE
Required Readings
Suggested Further Reading
- READING
Week 8 Machine Learning
This week we will look at modern and advanced analytic methods broadly called machine learning, or statistical pattern analysis. These methods are of great interest in the imaging community as they offer high sensitivity, the ability to explore activity at the systems level and the potential for predictive analysis and brain reading.
Monday 2/21/11 - Presidents Day.
Suggested Further Reading
Wednesday 2/23/11 - PCA, ICA, Machine learning. Speaker: Alan Yuille
OUTLINE
Required Readings
- READING
Suggested Further Reading
- READING
Week 9 Functional Connectivity, Multimodal Integration
WEEKLYSUMMARY
Monday 2/28/11 - Functional Connectivity. Speaker: Agatha Lenartowicz
OUTLINE Required Readings
- READING
Suggested Further Reading
- READING
Wednesday 3/2/11 - Multimodal Integration. Speaker: Cohen
OUTLINE Required Readings
- READING
Suggested Further Reading
- READING
Week 10 tbd
This week is presently left open for added topics and makeup as needed.
Monday 3/7/11 - tbd. Speaker: tbd
OUTLINE Required Readings
- READING
Suggested Further Reading
- READING
Wednesday 3/9/11 - tbd. Speaker: Cohen
Additional topics and wrapup. Required Readings
- READING
Suggested Further Reading
- READING